CheekAge Explorer
Welcome! You can use this tool to explore a large human buccal dataset in the context of a lifestyle and demographic survey and to run predictions on methylation EPIC data.
The Methylation tab will let you plot specific CpGs as a function of age or delta CheekAge, the Explore tab can be used to generate custom plots from lifestyle, demographic, technical, and predicted data, and the Prediction tab can be used to run the CheekAge clock on your own methylation data.
For more info please see the CheekAge: A novel next-generation buccal epigenetic aging clock associated with lifestyle and health.
To download a sample dataset for prediction please right-click and save this sample dataset.
If you have a larger dataset you would like to process, please reach out to [email protected] to set up a collaboration.
Note: TallyHealth does not collect data uploaded for use with this tool. All data are deleted after loading into memory.
Disclaimer: This tool is provided for academic use only.
Disclaimer 2: The CheekAge prediction module assumes beta or M-value EPIC methylation data from buccal cells.
Select axis and use sliders to explore data
Total samples:
Age prediction results will appear here.
The upload limit is ~ 100 mb. If you have bigger files to process, please separate them into smaller files and select all of them during upload. You may need to run in batches of about 200 samples max. Zip and gz compressed files should work as well. If the app crashes upon file upload, this may indicate a permission issue with the files uploaded or problems with the formatting. Also, we recommend converting beforehand to Ms and uploading with at least 3 significant digits.
Sample dataset [format your file like this]:
You can copy the results table and paste into Excel or similar spreadsheet editor as formatted text.